We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
Most Useful Reviews
9
Fatigue alleviated
5 people found this helpful
This magnesium has been wonderful! I've ordered it for myself and my daughter. It has completely removed the fatigue I previously felt by the end of the day. Additionally, I've noticed an improvement in my concentration. Remarkably, the effects appeared quite quickly and it's worth every penny.
Read More
9
Increased efficiency noted
1 people found this helpful
Prescribed by my doctor for chronic fatigue syndrome and concentration issues, I've been taking this magnesium for two months with exceptional results. My efficiency has increased, mood stabilised, and there's a notable absence of irritability. I'm also managing multiple projects at work, which I enjoy. I plan to discuss with my doctor its possible use for my children as well; I believe it could be helpful in their studies. I take three capsules each day. Highly recommend!
Read More
9
Fatigue symptoms reduced
1 people found this helpful
Struggling with insomnia, I wanted to try a magnesium supplement for my health. It's great that my feelings of fatigue have dissipated since starting this product.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
Read More
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
Read More
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
We explored the effects of magnesium on chronic fatigue syndrome (CFS), a condition marked by extended periods of debilitating fatigue. While there’s no definitive therapy established for CFS, our review of clinical trials reveals that magnesium treatment has shown promise, enhancing the well-being of some patients.
Other treatments like acyclovir have proven ineffective, and although intravenous immunoglobulin therapy shows potential, its results remain debated. We recognize that restoring immune function may be a piece of the puzzle, but overall, the effectiveness of magnesium for treating CFS symptoms is yet to be firmly established.
Read More
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 14 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Fatigue alleviated
5 people found this helpful
This magnesium has been wonderful! I've ordered it for myself and my daughter. It has completely removed the fatigue I previously felt by the end of the day. Additionally, I've noticed an improvement in my concentration. Remarkably, the effects appeared quite quickly and it's worth every penny.
Read More
9
Increased efficiency noted
1 people found this helpful
Prescribed by my doctor for chronic fatigue syndrome and concentration issues, I've been taking this magnesium for two months with exceptional results. My efficiency has increased, mood stabilised, and there's a notable absence of irritability. I'm also managing multiple projects at work, which I enjoy. I plan to discuss with my doctor its possible use for my children as well; I believe it could be helpful in their studies. I take three capsules each day. Highly recommend!
Read More
9
Fatigue symptoms reduced
1 people found this helpful
Struggling with insomnia, I wanted to try a magnesium supplement for my health. It's great that my feelings of fatigue have dissipated since starting this product.
Read More
10
Immediate energy boost
Magnesium is quite costly, but the price is justified. The effects are felt immediately; I sleep well and experience no fatigue, feeling good throughout the day, especially after giving birth when my body was weak and I felt drowsy.
Read More
9
No more fatigue
24 people found this helpful
I can't let go of this. It's my number one supplement that I must keep in stock. Since starting magnesium, I've been free of evening fatigue, irritation, and insomnia. I take 1 capsule in the afternoon and 2 before bed for optimal results.
Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis (ME), is a complex and debilitating condition characterized by profound fatigue that doesn’t improve with rest and worsens with physical or mental activity. This crippling fatigue is often accompanied by a variety of symptoms, including sleep disturbances, cognitive difficulties, muscle pain, and joint pain. Unlike typical tiredness, the fatigue experienced in CFS is long-lasting, and it can significantly hinder everyday activities and overall quality of life.
The precise cause of CFS remains unknown, but it is believed to be influenced by a combination of genetic, environmental, immunological, and psychological factors. Diagnosis primarily relies on a careful assessment of symptoms, as there are no definitive laboratory tests available. Treatment options focus on symptom management and may include lifestyle changes, physical therapy, medication for pain management, and cognitive behavioral therapy. Given the complexity and variability of the condition, individuals with CFS should consult healthcare professionals who specialize in this area to develop personalized management strategies.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
While there is ongoing research into the potential benefits of magnesium for various health conditions, including Chronic Fatigue Syndrome (CFS), definitive conclusions remain elusive. Magnesium plays a critical role in energy production, muscle function, and overall metabolism, which suggests it may provide some support for those suffering from CFS. Some anecdotal evidence and small-scale studies suggest that magnesium supplementation could help alleviate certain symptoms associated with fatigue, particularly if a deficiency is present. However, further extensive clinical studies are needed to establish a clear link between magnesium supplementation and improvement in CFS symptoms.
It's important for individuals considering magnesium supplementation to consult with a healthcare professional. They can determine individual needs and whether magnesium may be beneficial based on personal health profiles and existing conditions. Additionally, magnesium should not be viewed as a standalone solution for Chronic Fatigue Syndrome; a comprehensive approach that includes lifestyle changes, a balanced diet, and other treatments may be necessary for managing symptoms effectively.
Based on user reviews, many individuals taking magnesium supplements for Chronic Fatigue Syndrome report positive results within just a few days to a few weeks. For instance, one user noted that they experienced significant relief from fatigue after just one night of taking the supplement Read Review. Another user mentioned they felt more energetic and less fatigued after a few weeks of use, which they attributed to the supplement's quality Read Review.
Additionally, some users indicated that after two months of consistent use, they observed exceptional improvements in their energy levels and overall mood Read Review. Other reviewers emphasized a noticeable decrease in fatigue when taking the supplement regularly, suggesting that the cumulative effects may lead to significant improvements over time Read Review. Overall, while individual experiences may vary, many users experience beneficial effects relatively quickly, enhancing their energy levels and reducing fatigue.
The evidence supporting the use of magnesium for Chronic Fatigue Syndrome (CFS) is mixed, with some studies indicating potential benefits but not without limitations. A systematic review of complementary and alternative therapies found that while magnesium showed promise, the overall effectiveness of various treatments remains limited due to small sample sizes and inherent biases in the studies [1]. Further, another investigation revealed that while magnesium deficiency was prevalent among patients with unexplained fatigue, supplementation did not significantly enhance antioxidant activity or reduce fatigue levels meaningfully [2].
Additionally, some case studies have reported positive outcomes with magnesium treatment. For instance, one case demonstrated that intravenous magnesium sulfate administration led to a notable reduction in fatigue and improved functioning in a patient after other treatments failed [3]. Moreover, a controlled trial indicated that those receiving magnesium showed significant improvements in energy and emotional well-being compared to a placebo [5]. Therefore, while there are individual cases and some studies suggesting magnesium could benefit CFS symptoms, further rigorous research is needed to establish its effectiveness as a reliable treatment option.
Based on user reviews, many individuals have reported significant improvements in their symptoms after incorporating magnesium supplements into their routine. Users have cited faster resolutions to fatigue, with one reviewer mentioning that their fatigue disappeared shortly after starting the supplement, leading to a newfound sense of energy and improved concentration Read Review. Another user, who had been prescribed magnesium for chronic fatigue syndrome, noted exceptional results after two months, highlighting enhanced efficiency and stabilization of mood alongside diminished irritability Read Review.
Numerous users have also reported noticeable enhancements in their sleep quality and a reduction in anxiety-related symptoms. For instance, after taking magnesium, one reviewer found relief from insomnia and fatigue post-childbirth Read Review. Similarly, another user dealing with post-Covid symptoms remarked on improvements in sleep and a calming effect after incorporating magnesium into their health regimen Read Review. Overall, while individual experiences vary, the collective feedback suggests that magnesium supplements can lead to significant improvements in energy levels and cognitive functions.
Users report a variety of experiences when combining magnesium supplements with other dietary aids to manage Chronic Fatigue Syndrome. For instance, one reviewer noted that taking magnesium along with additional forms helped them feel calmer and boosted their sleep and memory after experiencing post-Covid symptoms Read Review. This suggests that for some, the synergistic effects of magnesium with other supplements might enhance overall effectiveness in combating fatigue. Additionally, another user highlighted that the combination of magnesium with vitamins and minerals led to a significant boost in their energy levels and reduction in fatigue, particularly during a challenging autumn-winter season Read Review.
Conversely, while several reviews emphasize the benefits of magnesium alone, others imply that combining it with other nutritional approaches may provide enhanced results. For example, one user mentioned a comprehensive health approach involving multiple vitamins and minerals, which they believe contributed to their increased energy and improved well-being Read Review. Overall, while individual results may differ, many users find that incorporating magnesium into a broader supplement regimen can yield positive outcomes in managing chronic fatigue symptoms.
Users have reported positive results regarding magnesium as a treatment for Chronic Fatigue Syndrome, with many finding specific dosages effective in alleviating their symptoms. For instance, one user mentioned taking three capsules daily and noted significant improvements in both energy levels and mood stability over a two-month period, attributing these results to their prescribed magnesium supplement Read Review. Another user shared an effective regimen of taking 1 capsule in the afternoon and 2 before bed, which they found ideal for combating evening fatigue and insomnia Read Review.
Several users highlighted that magnesium not only alleviates fatigue but also promotes better sleep quality and enhances overall well-being. For example, one user stated they felt a noticeable energy boost and relief from fatigue after using the product Read Review. Another user, who managed to combat fatigue while also experiencing insomnia, reported feeling refreshed and alert after improving their magnesium intake Read Review. Overall, user experiences suggest that individual dosage may vary, but many find success with regular intake of magnesium supplements.
7.5
Fatigue relief achieved
1 people found this helpful
The night I slept with Life Extension Magnesium, I felt refreshed with significant relief from my fatigue.
7.5
Increased energy levels
I purchased vitamins to boost my overall health and immunity. After a few weeks, I feel more energetic and less fatigued, which enhances my overall well-being, especially during the autumn-winter season. The quality of the ingredients is commendable; they are easy to swallow and leave no unpleasant aftertaste. They are well absorbed and have no side effects, which is crucial for me.
9
Increased efficiency noted
1 people found this helpful
Prescribed by my doctor for chronic fatigue syndrome and concentration issues, I've been taking this magnesium for two months with exceptional results. My efficiency has increased, mood stabilised, and there's a notable absence of irritability. I'm also managing multiple projects at work, which I enjoy. I plan to discuss with my doctor its possible use for my children as well; I believe it could be helpful in their studies. I take three capsules each day. Highly recommend!
9
Reduced fatigue symptoms
This is a great supplement that alleviates nervous and muscle tension. I noticed signs of magnesium deficiency like cravings, muscle cramps, poor sleep, and fatigue. Normal magnesium intake is difficult through food alone, especially with alcohol and caffeine affecting levels. I've been taking magnesium for two years, and it's truly transformed my life, moving me from constant fatigue to a much calmer state.
9
Fatigue alleviated
5 people found this helpful
This magnesium has been wonderful! I've ordered it for myself and my daughter. It has completely removed the fatigue I previously felt by the end of the day. Additionally, I've noticed an improvement in my concentration. Remarkably, the effects appeared quite quickly and it's worth every penny.
10
Immediate energy boost
Magnesium is quite costly, but the price is justified. The effects are felt immediately; I sleep well and experience no fatigue, feeling good throughout the day, especially after giving birth when my body was weak and I felt drowsy.
8
Increased calmness
1 people found this helpful
Following mild Covid, I experienced post-Covid syndrome with weakness and sleep problems. While taking magnesium and other forms, I've noticed becoming calmer and improvements in sleep and memory. I struggled with severe headaches, but magnesium has been a lifesaver.
9
Lighter body feeling
It appears worth the steep price. Since I started taking vitamins and minerals, I no longer feel fatigue, and my body feels lighter.
9
No more fatigue
24 people found this helpful
I can't let go of this. It's my number one supplement that I must keep in stock. Since starting magnesium, I've been free of evening fatigue, irritation, and insomnia. I take 1 capsule in the afternoon and 2 before bed for optimal results.
7.5
Energy boost experienced
This product copes exceptionally well with fatigue and provides a noticeable energy boost!
4
Limited magnesium effectiveness in CFS
Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review.
We systematically reviewed randomized controlled trials on complementary and alternative medicine (CAM) treatments for chronic fatigue syndrome (CFS).
Although 26 studies involving over 3,000 participants explored various therapies, the findings showed limited effectiveness overall.
While some treatments like massage and specific dietary supplements had some positive effects, most failed to provide significant benefits.
Notably, magnesium showed potential, but due to small sample sizes and biases in the studies, we can't make firm conclusions just yet. More rigorous studies are needed to confirm these effects.
7
Magnesium shows limited benefit for fatigue
Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium.
We investigated how magnesium levels relate to chronic fatigue by studying 93 patients with unexplained fatigue.
Around 47% of participants showed magnesium deficiency, linked to reduced plasma antioxidant capacity.
Although magnesium supplementation didn't increase blood glutathione levels, we observed improved magnesium stores and vitamin E levels.
However, this did not equate to a significant boost in antioxidant activity or a decrease in lipid vulnerability. Therefore, while magnesium may help improve some parameters, it is not a panacea for chronic fatigue syndrome.
7
Magnesium sulfate shows potential benefits
[A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate].
We aimed to understand the effects of magnesium sulfate treatment on a patient with chronic fatigue syndrome. The case involved a 29-year-old woman experiencing severe fatigue alongside various symptoms, including swelling lymph nodes and muscle pain.
After other treatments failed to provide relief, we administered magnesium sulfate intravenously once a week. Remarkably, after six weeks, the patient reported a significant reduction in fatigue and improved daily functioning, eventually leading to her discharge from the hospital.
8
Magnesium potentially benefits CFS patients
Red blood cell magnesium and chronic fatigue syndrome.
We investigated the relationship between magnesium levels in red blood cells and chronic fatigue syndrome (CFS). A case-control study revealed that CFS patients had lower magnesium levels than healthy individuals.
In a randomized, double-blind trial, 32 CFS patients received either magnesium sulphate or a placebo for six weeks. Those treated with magnesium reported significant improvements in energy, emotional wellbeing, and pain relief, with twelve out of fifteen feeling better.
In contrast, only three out of seventeen patients on placebo reported any improvement. Overall, these findings suggest that magnesium treatment may positively impact the wellbeing of those suffering from CFS.
References
Alraek T, Lee MS, Choi TY, Cao H, Liu J. Complementary and alternative medicine for patients with chronic fatigue syndrome: a systematic review. BMC Complement Altern Med. 2011;11:87. doi:10.1186/1472-6882-11-87
Manuel y Keenoy B, Moorkens G, Vertommen J, Noe M, Nève J, et al. Magnesium status and parameters of the oxidant-antioxidant balance in patients with chronic fatigue: effects of supplementation with magnesium. J Am Coll Nutr. 2000;19:374.
Takahashi H, Imai K, Katanuma A, Sugaya T, Hisano K, et al. [A case of chronic fatigue syndrome who showed a beneficial effect by intravenous administration of magnesium sulphate]. Arerugi. 1992;41:1605.
Uchida A. [Therapy of chronic fatigue syndrome]. Nihon Rinsho. 1992;50:2679.
Cox IM, Campbell MJ, Dowson D. Red blood cell magnesium and chronic fatigue syndrome. Lancet. 1991;337:757.